About ADM Biopolis

About
ADM Biopolis
About ADM Biopolis

We cover the whole process

DISCOVER & IDENTIFICATION

– Sourcing: samples from healthy humans (e.g. faeces of babies < 3 months old) 

– Species identifications: 16S rRNA

– Whole genome sequencing

FUNCTIONALITY SCREENING & VALIDATION

– Survival under physiological conditions: pH, bile salts

– Target functionality: in vitro models, animals, clinical trials

SAFETY ANALYSIS

In vitro and in vivo studies following EFSA and WHO/FAO guidelines: antibiotic resistance, toxins & pathogenicity, animal models, additional testing upon request

SCALE-UP

– Optimization of production parameters: from 1L to pilot, freeze drying, specific formulations, stability testing.

PRODUCTION

– Packaging

– GMP, Kosher and halal

– Non-GMO and Vegan

– FSMA compliant

We cover the whole process

DISCOVER & IDENTIFICATION

– Sourcing: samples from healthy humans (e.g. faeces of babies < 3 months old) 

– Species identifications: 16S rRNA

– Whole genome sequencing

FUNCTIONALITY SCREENING & VALIDATION

– Survival under physiological conditions: pH, bile salts

– Target functionality: in vitro models, animals, clinical trials

SAFETY ANALYSIS

In vitro and in vivo studies following EFSA and WHO/FAO guidelines: antibiotic resistance, toxins & pathogenicity, animal models, additional testing upon request

SCALE-UP

– Optimization of production parameters: from 1L to pilot, freeze drying, specific formulations, stability testing.

PRODUCTION

– Packaging

– GMP, Kosher and halal

– Non-GMO and Vegan

– FSMA compliant

Our unique methodology
Safety first

When finding novel probiotic strains, safety is the first thing that we consider. We have gone the extra mile to ensure that all of our strains go through the highest quality standards, ensuring that no undesired gene or metabolic activities are present in our products. We guarantee safety by complementary approaches, using whole-genome sequencing, biochemistry experiments and animal trials.

Belonging to QPS species from:
-Bifidobacteria
-Lactobacillus

Able to survive intestinal tract
-Low pH
-Bile salts

No production of undesired molecules
-D-lactate
-Biogenic amines
-No deconjugation of bile salts

Antibiotic resistance assessed according to EFSA guidelines

Acute ingestion study in immunocompetent and immunosuppressed mice

Whole genome sequencing and validation

Our steps to ensure top products

Define Health Target

Microbiome relation

Set Probiotic Goals

Set Probiotic Goals

Scalability Trials

Strain/consortia design

Murine Clinical Trials

Human Clinical Trials

Top Class Products

We know that we are only half human – the human body has 39 trillion bacterial cells vs. 30 trillion human cells. There is an estimated 40,000 bacterial species in the human gut, making the gastrointestinal tract the largest immune organ in our body. The majority of our bacteria reside in the colon, with the skin being the second most abundant site.

This is why at ADM Biopolis, we aim to understand the complex relationship between microbiome and health. Our sequencing technology has enabled us to identify and understand this microbial diversity. There are a different number of health indications that are completely related to our microbial behavior and to our microbiome.

We approach the development of microbiome solutions in a comprehensive way. We isolate, select, develop, and produce the right strains to initiate the specific alteration of the microbiome (dysbiosis) that is responsible for a particular health indication.

Digestive & Gut Health, Inflammation, Celiac Disease

10 SCI* publications

Immune System

9 SCI* publications

Atopic Dermatitis

2 SCI* publications

Digestive & Gut Health, Inflammation, Celiac Disease

10 SCI* publications

Immune System

9 SCI* publications

Atopic Dermatitis

2 SCI* publications

Rotavirus

5SCI* publications

Metabolic Syndrome

5 SCI* publications

PSORIASIS

2SCI* publications

Helicobacter Pylori

1 SCI* publications

Vaginosis

1 SCI* publications

Male fertility

1SCI* publications

Our scientific approach and unique methodology has enabled us to come up with disruptive science driven results in a number of various health targets or indications.

The quality of our research thus our publications is outstanding, publishing all our work on Science Citation Index journals.

*SCI: The Science Citation Index is the citation index that describes the world’s leading journals in science, because of a rigorous selection process

Our commitment with quality

In 2014 we started our certification policy in order to ensure the highest level of quality in our probiotics. In this regard, we can proudly state that we have accomplished all the top quality certifications.

Standardization is also crucial for us. Availability and Packaging as well as documentation and logistics (transport, storage and
stability) comprises one of the most important stages.

Documentation & Certificates

_Certificate of analysis (CoA)
_Material safety data sheet (MSDS)
_GMO free certificate
_BSE/TSE free declarations
_Stability Data
_Product Data Sheet
_HALAL, KOSHER certification
_QPS, GMP, ISO 9001:2015, FSSC 22000, ISO 14001:2015,
_Allergen-free, non-GMO, vegan

Availabilities & Packaging

_Product supplied in vacuum-sealed bags
_Bulk powder
_5·1010 and 1·1011 cfu/g as standard concentrations
_Refrigerated transport and storage (+2 °C to +8 °C)
_24 months stored at recommended temperature range

We understand society’s needs and trends

. All our probiotics are natural isolates and are not genetically modified 

. We source only non-GMO ingredients for manufacturing 

. We do not use any animal products in the manufacturing of our probiotics, so our products are naturally vegan 

. Our products do contain no gluten, corn, soy, milk, nuts or fish ingredients